This week's NFL slate is loaded with elite matchups.
Week 10 at a glance: Two unlikely MVP candidates, Drake Maye and Baker Mayfield, square off in Tampa Bay as the Buccaneers battle the New England Patriots. And on Monday, the Frozen Tundra is projected to have sub-zero temperatures when the Green Bay Packers host the Philadelphia Eagles.
Check out our NFL Week 10 betting guide for staff picks and predictions on the loaded 14-game slate.
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NFL Week 10 betting guide: predictions
ATS picks: Get ATS predictions from five different staff writers on every game of the week.
NFL Week 10 best bets: The 10th NFL Sunday of the season kicks off in Berlin, Germany, and Jordan Horrobin has his eyes on Kyle Pitts. Find out why, and get two ATS picks plus a moneyline bet.
Upset picks: Green Bay just lost as 14-point favourites to the Carolina Panthers, and Philadelphia is coming off a bye. That seems like a perfect recipe for the Eagles to pull off an upset.
Raiders vs. Broncos TNF picks: Las Vegas has the 29th-ranked scoring offence ... but Horrobin thinks the pendulum has swung too far on its team total.
Raiders vs. Broncos TNF SGP: Brock Bowers didn't miss a beat returning from the IR last week, and factors into this +400 SGP that also features Troy Franklin.
NFL prop bets: Drake Maye is making a case to win MVP in his sophomore season. He's featured in this week's prop bets, along with picks on Sam LaPorta and Michael Wilson.
NFL Week 10 betting notes
- Dan Campbell and Jared Goff have won and covered 12 straight games following a loss. The Detroit Lions are 8-point road favourites against the Jayden Daniels-less Washington Commanders.
- Maye (+400) and Mayfield (+1,500) are in MVP contention as the Patriots and Buccaneers top their respective divisions. New England's QB ranks fifth in passing yards (2,285) and QBR (74.0), while Mayfield has engineered four fourth-quarter comebacks.
- It's Josh Allen (+175), though, who tops the MVP odds board through eight games. He's won seven straight games against the Miami Dolphins, this week's opponent, while throwing 20 passing TDs.
-> Don't miss out — bet on NFL Week 10 here!
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- The Carolina Panthers are 5-4 ... but they've failed to cover or win 10 straight games as a favourite (dating back to Sept. 2021).
- Jalen Hurts and the Eagles are 4-0 SU and ATS as an underdog since the start of last season. The Packers are 3-5 ATS as a favourite this year, losing two of those games outright with a tie.
Biggest spreads: Bills (-9.5) vs. Dolphins; Raiders vs. Broncos (-9); Lions (-8) vs. Commanders
Highest totals: Bills vs. Dolphins (50.5); Rams vs. 49ers (49.5); Lions vs. Commanders (49)
NFL Week 10 matchups
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-> Bet on Hurts and Love at NorthStar Bets!
Thursday Night Football (Nov. 6)
- Raiders vs. Broncos
Sunday, Nov. 9: NFL London Game (9:30 a.m. ET)
- Falcons vs. Colts
Sunday, Nov. 9: 1 p.m. ET slate
- Ravens vs. Vikings
- Patriots vs. Buccaneers
- Jaguars vs. Texans
- Browns vs. Jets
- Saints vs. Panthers
- Giants vs. Bears
- Bills vs. Dolphins
Sunday, Nov. 9: 4 p.m. ET slate
- Cardinals vs. Seahawks
- Rams vs. 49ers
- Lions vs. Commanders
Sunday Night Football
- Steelers vs. Chargers (8:20 p.m. ET)
Monday Night Football (Nov. 10)
- Eagles vs. Packers (8:15 p.m. ET)
Week 10 byes: Cincinnati Bengals, Dallas Cowboys, Kansas City Chiefs, Tennessee Titans
