Bye weeks, be gone. We're back to a full slate of NFL action for the remaining weeks of the 2025 season.
The Week 15 narrative: Lopsided matchups are plentiful this weekend, with six of 13 favourites on Sunday afternoon laying 7.5 points or more. That includes both the Seattle Seahawks and San Francisco 49ers, who are wrestling for position in the crowded NFC West.
Check out our staff's NFL Week 15 ATS picks for predictions on every game.
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NFL Week 15 ATS picks
NorthStar Bets' Avery Perri, Jordan Horrobin, Spencer Closs, Chris Toman and Steven Psihogios offer up their NFL Week 15 ATS picks for all 16 games.
NFL odds as of 10 a.m. ET on Thursday, Dec. 11, 2025.
Thursday Night Football pick
Falcons vs. Buccaneers (Thursday, Dec. 11: 8:20 p.m. ET)
NorthStar Bets line: Tampa Bay -4.5
Horrobin says: Neither of these teams is riding high into Week 15, but I'm hoping the expectant return of Mike Evans can provide the home team with some juice. The Falcons are 1-7 straight up (2-5-1 ATS) in their past eight games, and they lost at home to the Bucs in the season opener. Given that Tampa is set to play its third straight home game, it should be the more rested team.
Staff picks: Perri (TB) | Horrobin (TB) | Closs (TB) | Toman (TB) | Psihogios (ATL)
-> Place your bets on the Week 14 slate
NFL ATS picks: The early Sunday slate
Cardinals vs. Texans (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Houston -9.5
Toman says: Houston's elite defence held the Chiefs to 10 points in Week 14, covering this number to win its fifth game in a row. Since beginning the season 0-3, the Texans are 8-2 straight up, which includes several games without starting QB CJ Stroud. This is a big number, but the dreadful Cardinals have lost by 19-plus points three times in their last five. They have one victory since Week 2.
Staff picks: Perri (HOU) | Horrobin (HOU) | Closs (HOU) | Toman (HOU) | Psihogios (ARI)
Ravens vs. Bengals (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Baltimore -2.5
Perri says: Cincinnati has won seven of its last eight games where Burrow has played start to finish. The outlier was last week's 39-34 loss in Buffalo, where the Bengals squandered a 10-point fourth-quarter lead. I fully believe Burrow can out-duel Lamar Jackson at home. Jackson is clearly playing hurt and has a 55.6 completion percentage with three total TDs and six turnovers since Nov. 1.
Staff picks: Perri (CIN) | Horrobin (CIN) | Closs (BAL) | Toman (BAL) | Psihogios (BAL)
Bills vs. Patriots (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Buffalo -1
Closs says: The Bills have been inconsistent this season, even with a weak schedule. Buffalo has nine wins, but six have come against teams currently below .500, and the team is 3-3 on the road. New England has the best record in the NFL (11-2) and is currently on a 10-game heater. When these two met earlier this season in Buffalo, the Pats handed the Bills their only home loss of the season. I believe they can replicate that performance, especially at Gillette Stadium.
Staff picks: Perri (BUF) | Horrobin (NE) | Closs (NE) | Toman (BUF) | Psihogios (BUF)
Browns vs. Bears (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Chicago -7.5
Toman says: I don't love this number, but I don't have much confidence in the Browns' ability to score. The Bears are 9-4, though not many of those victories have been in blowout fashion. They are due. At home vs. a Browns team coming off a straight-up loss to the Titans, this is about as comfortable a spot as you can find.
Staff picks: Perri (CLE) | Horrobin (CLE) | Closs (CHI) | Toman (CHI) | Psihogios (CLE)
Chargers vs. Chiefs (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Kansas City -5.5
Horrobin says: It feels like Kansas City has been playing must-win games for weeks, and the team has consistently come up empty. The Chiefs are on a five-game losing skid, dropping four of those games outright as favourites. The Chargers are on a short week, but this is a hearty sum of points to back a team that beat KC on a neutral field (as a 3-point underdog) in Week 1.
Staff picks: Perri (KC) | Horrobin (LAC) | Closs (KC) | Toman (LAC) | Psihogios (LAC)
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Raiders vs. Eagles (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Philadelphia -11
Closs says: Both Geno Smith (doubtful) and Max Crosby (questionable) could miss this game, immediately giving the Eagles a huge edge. Crosby is one of the elite defensive ends in the NFL, and backup quarterback Kenny Pickett has yet to make a start this season. The Raiders have lost seven straight games with a pitiful 1-5 record on the road. The Eagles have lost three straight against teams in the playoff hunt. Las Vegas is already looking ahead to the draft, so this is the perfect opponent for Philly to get back on track.
Staff picks: Perri (LV) | Horrobin (PHI) | Closs (PHI) | Toman (LV) | Psihogios (LV)
Jets vs. Jaguars (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: Jacksonville -13
Toman says: Before last week's 24-point loss to the Dolphins, the Jets had gone 8-0-2 against this number over their last 10. They don't win much, but they've hung around many games and been solid against the spread (7-5-1). The Jaguars are cooking, taking advantage of an extremely favourable run of games since their Week 8 bye. But they haven't been more than a 6-point favourite all season, and I'm not comfortable taking them to win by a pair of TDs.
Staff picks: Perri (JAX) | Horrobin (NYJ) | Closs (NYJ) | Toman (NYJ) | Psihogios (NYJ)
Commanders vs. Giants (Sunday, Dec. 14: 1:00 p.m. ET)
NorthStar Bets line: New York -2.5
Horrobin says: When two awful teams square off, I typically bank points with the underdog. But after the Commanders got shut out in Minnesota last week, I can't put my faith in Marcus Mariota and Co. The Giants are at least showing some fight, with one-score losses against the Lions, Packers and Bears over the past four weeks. Washington has only covered a +2.5 spread once in its past seven games.
Staff picks: Perri (NYG) | Horrobin (NYG) | Closs (NYG) | Toman (NYG) | Psihogios (NYG)
NFL 4 p.m. slate
Panthers vs. Saints (Sunday, Dec. 14: 4:25 p.m. ET)
NorthStar Bets line: Carolina -2.5
Closs says: I'm siding with the underdog in this divisional matchup. Tyler Shough is keeping the Saints in games, and he already led his team to a win over the Panthers in Week 10. What stands out from that game, however, was the Saints holding the Panthers to seven points. Since that contest, New Orleans has allowed 18.0 PPG, so I expect its defence to be the difference again. The Saints are 2-2 over their last four games.
Staff picks: Perri (NO) | Horrobin (NO) | Closs (NO) | Toman (CAR) | Psihogios (CAR)
Lions vs. Rams (Sunday, Dec. 14: 4:25 p.m. ET)
NorthStar Bets line: Los Angeles -5.5
Perri says: Detroit is one of the few teams that can keep up with L.A.'s high-flying offence. The Lions are averaging 30.3 PPG, the most in the NFL, and are coming off a 44-point outburst on TNF in Week 14. That extra rest, combined with SoFi Stadium's propensity to be overrun by visiting fans, should mitigate Detroit's road disadvantage. Dan Campbell's squad is 2-0 against the Rams in the last two years.
Staff picks: Perri (DET) | Horrobin (LAR) | Closs (DET) | Toman (DET) | Psihogios (DET)
Packers vs. Broncos (Sunday, Dec. 14: 4:25 p.m. ET)
NorthStar Bets line: Green Bay -2
Horrobin says: It's tough to bet against Denver as an underdog amid a 10-game win streak. But I'm doing it anyway. Green Bay never trailed last week against the Bears en route to taking the top spot in the NFC North, and the Packers have won their past four road games by a combined 28 points. Denver is 3-5-0 ATS in its past eight games and has a worse point differential than Green Bay.
Staff picks: Perri (GB) | Horrobin (GB) | Closs (GB) | Toman (DEN) | Psihogios (DEN)
Colts vs. Seahawks (Sunday, Dec. 14: 4:25 p.m. ET)
NorthStar Bets line: Seattle -14
Horrobin says: Somehow, 44-year-old Philip Rivers — who hasn't thrown an NFL pass since 2020 — appears lined up to start for the Colts this weekend. Crazier things have happened, I guess, but it's impossible for me to see that going well. The Seahawks have the NFL's best point differential (+161) and ATS record (10-3-0), and they've covered a -14 spread in four of their past six games.
Staff picks: Perri (SEA) | Horrobin (SEA) | Closs (SEA) | Toman (SEA) | Psihogios (SEA)
Titans vs. 49ers (Sunday, Dec. 14: 4:25 p.m. ET)
NorthStar Bets line: San Francisco -13
Perri says: The Titans got their win last week, and now travel west to take on the Niners coming off a bye. I think this will get very ugly. Tennessee had lost seven straight before beating Cleveland with a -90 point differential. San Fran's offence, meanwhile, is rounding into form with Brock Purdy back at the helm. Christian McCaffrey should carve up the league's 27th-ranked defence by EPA per play.
Staff picks: Perri (SF) | Horrobin (SF) | Closs (TEN) | Toman (SF) | Psihogios (SF)
Sunday and Monday Night NFL Week 15 ATS picks
Vikings vs. Cowboys (Sunday, Dec. 14: 8:15 p.m. ET)
NorthStar Bets line: Dallas -6
Perri says: I'm bullish on Dallas winning this game by multiple scores. The Cowboys are 3-1 since their bye week, toppling the reigning AFC and NFC champions. They just lost 44-30 to the Lions in Detroit, but the Vikings aren't anywhere near their divisional rivals in terms of talent. J.J. McCarthy's overall numbers are still horrendous, and he shouldn't be able to keep pace with the Cowboys' top-five offence.
Staff picks: Perri (DAL) | Horrobin (DAL) | Closs (DAL) | Toman (MIN) | Psihogios (MIN)
Dolphins vs. Steelers (Monday, Dec. 15: 8:15 p.m. ET)
NorthStar Bets line: Pittsburgh -3.5
Perri says: Tua Tagovailoa in cold weather ... what could go wrong? I'm hoping a lot. Tua is 0-5 SU and 1-4 ATS in games contested under 40 Fahrenheit (4.4 °C), per Action Network. Monday's primetime game is projected to be played at -7.2 °C. Pittsburgh just picked up its biggest win of the season, toppling the Ravens in Baltimore to take the AFC North lead. The Steelers should keep rolling in primetime.
Staff picks: Perri (PIT) | Horrobin (PIT) | Closs (PIT) | Toman (MIA) | Psihogios (MIA)
NFL ATS picks: Week 14 + season records
- Closs: 6-8-0 (100-102-6)
- Psihogios: 6-8-0 (100-102-6)
- Toman: 8-6-0 (100-102-6)
- Perri: 4-10-0 (94-108-6)
- Horrobin: 6-8-0 (92-110-6)
