Giants vs. Patriots Week 13 Monday Night Football picks: Bet on New York to cover, Maye to run

Bet on Drake Maye to run often against the New York Giants. Photo by Greg M. Cooper/AP.
Bet on Drake Maye to run often against the New York Giants. Photo by Greg M. Cooper/AP.

It's a double Super Bowl rematch as the New York Giants and New England Patriots square off on Monday Night Football.

The pregame narrative: Many football fans recall the clashes between Eli Manning and Tom Brady fondly. Now, Jaxson Dart and Drake Maye carry the torch for these franchises. The two look to put on a show in prime time.

Check out my Giants vs. Patriots picks for Dec. 1, featuring a prop bet on Maye.

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Giants vs. Patriots picks

Best Bet: Giants +7.5 (-120)

New York got some positive news in the quarterback room this week: Dart has cleared concussion protocol and will play in Week 13.

But his reinsertion into the lineup isn't why I'm backing the Giants in this contest.

No, it has to do with some injury news from the Patriots.

New England has been one of the healthiest teams in the NFL this season, but it suffered a pair of significant blows in Week 12.

Left guard Jared Wilson and left tackle Will Campbell both went down with injuries and will miss Monday Night Football.

That's bad news against a Giants team that can get after the QB.

New York is 12th in QB pressures this year (96) and eighth in QB knockdowns (39).

The Giants should be able to put pressure on Maye and make him uncomfortable in this contest.

Key stat: New York has covered this spread in three consecutive games.

-> Back the Giants against to cover at NorthStar Bets

MNF over/under prediction

Under 46.5 points (-110): There are a couple of factors that play into my under pick.

The first is the offensive line injuries for the Patriots. Maye is tied for the NFL lead in 20-plus yard completions with 45. The injuries to the left side of the line will make it hard for Maye to hold the ball long enough for those routes to develop.

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Expect that to negatively impact New England's offensive output.

Secondly, the switch from Jameis Winston to Dart will also likely limit New York's point total.

Winston's free-wheeling style tends to lead to higher point totals, but losing that isn't the only reason why New York's ceiling is capped.

A big part of Dart's game is his rushing ability. I don't expect the young QB to take off much in his first game back from a concussion.

Expect Dart to rush less and for New York to score fewer points.

Maye over 21.5 rushing yards (-112): This is a fair line for Maye considering his performances this year.

Maye has topped this line in six games, and he's fallen short of it in six games.

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This matchup, however, presents a great opportunity to back the over.

Firstly, the Giants are allowing the second-most rushing yards per game to opposing QBs (25.2).

Secondly, the offensive line injuries should cause Maye to leave the pocket more than he likes and scramble.

Back Maye to use his legs in prime time.

Giants vs. Patriots picks made at 3:35 p.m. ET Nov. 29, 2025.

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